CK2 Inhibitor

Structure-based design and synthesis of novel macrocyclic pyrazolo[1,5-a][1,3,5]triazine compounds as potent inhibitors of protein kinase CK2 and their anticancer activities>

Z. Nie, C. Perretta, P. Erickson, S. Margosiak, J. Lu, A. Averill, R. Almassy and S. Chu
Bioorganic & Medicinal Chemistry Letters (2008), Vol. 18 pages 619-623
Abstract

Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2

Z. Nie, C. Perretta, P. Erickson, S. Margosiak, R. Almassy, J. Lu, A. Averill, K.M. Yager and S. Chu
Bioorganic & Medicinal Chemistry Letters (2007), Vol. 17 pages 4191-4195
Abstract